Kangning base gel is a basement membrane matrix extracted from EHS mouse tumors rich in extracellular matrix proteins. Its main components include laminin, type IV collagen, nestin, heparin glycoprotein, as well as growth factors and matrix metalloproteinases.

At room temperature, the substrate gel polymerizes to form a biologically active three-dimensional matrix, simulating the structure, composition, physical properties, and function of the cell basement membrane in vivo, which is beneficial for cell culture and differentiation in vitro. It can be used for research on cell morphology, biochemical function, migration, invasion, and gene expression.